Over its many seasons, ‘Grey’s Anatomy’ has featured a large number of actors who have come and gone. Viewers often become invested in the doctors at Grey Sloan Memorial, making it bittersweet when characters leave the show to pursue other opportunities. Several of these actors have gone on to have successful careers in movies and other TV shows, while some have focused on stage work or directing. Looking at what they’re doing now shows they’re all working on a wide variety of projects in the entertainment world.
Patrick Dempsey
Patrick Dempsey left the medical drama after playing Dr. Derek Shepherd for eleven seasons. He then pursued his passion for auto racing and took on film roles, including appearing in ‘Bridget Jones’s Baby’. Dempsey later returned to TV with the series ‘Devils’ and the movie ‘Disenchanted’, and most recently starred as Piero Taruffi in the sports biopic ‘Ferrari’.
Sandra Oh
After ten seasons playing Dr. Cristina Yang, Sandra Oh moved on to explore different acting roles. She received widespread praise and several awards for her leading role in the thriller series ‘Killing Eve’. More recently, she’s lent her voice to animated films like ‘Over the Moon’ and ‘Turning Red’, and appeared in the comedy film ‘Quiz Lady’ as well as the series ‘The Sympathizer’.
Katherine Heigl
Katherine Heigl left the show Grey’s Anatomy during its sixth season after playing Dr. Izzie Stevens. She then focused on romantic comedies before returning to TV with the legal drama Suits. More recently, she starred in and produced the two-season drama Firefly Lane. Her next project is the thriller That’s Amore, where she’ll be acting alongside John Travolta.
Justin Chambers
Justin Chambers was a core cast member on the medical drama for sixteen seasons, playing Dr. Alex Karev. He decided to leave the show to pursue a wider range of acting opportunities and focus on his personal life. Recently, he took on the role of Marlon Brando in the miniseries ‘The Offer’, which tells the story of how ‘The Godfather’ was made. This was his first significant TV role since departing the medical series.
T.R. Knight
T.R. Knight departed his role as Dr. George O’Malley on the show to focus on stage acting. He later appeared in TV shows like ‘The Good Wife’ and the miniseries ‘11.22.63’. Knight worked with ‘Grey’s Anatomy’ creator Shonda Rhimes again on the series ‘The Catch’, and most recently had a recurring role in the mystery thriller ‘The Flight Attendant’.
Eric Dane
Eric Dane is known for playing Dr. Mark Sloan on the medical drama until his character left the show in its ninth season. He then starred as Tom Chandler in the action series ‘The Last Ship’. More recently, he’s gained recognition for his role as Cal Jacobs in the teen drama ‘Euphoria’. Dane has also appeared in films like the horror movie ‘The Ravine’ and the action film ‘Bad Boys: Ride or Die’.
Chyler Leigh
Chyler Leigh became well-known for her role as Dr. Lexie Grey on a medical drama, appearing for five seasons. Afterwards, she joined ‘Supergirl’ and played Alex Danvers for six seasons, later continuing the character in other shows set in that world. Currently, she stars in and helps produce the time travel series ‘The Way Home’.
Sara Ramirez
Sara Ramirez is an actor who became well-known for playing Dr. Callie Torres on a medical drama for ten seasons. After a period away from acting, they joined the cast of the political series ‘Madam Secretary’ as a main character. More recently, Ramirez starred as Che Diaz in the continuation of ‘Sex and the City,’ titled ‘And Just Like That…’. They are also a dedicated advocate for LGBTQ+ rights and continue to work on different acting roles.
Jesse Williams
I was a huge fan of Jesse Williams as Dr. Jackson Avery on Grey’s Anatomy for twelve seasons, and I’ve been so impressed watching his career take off since then! He’s really proven himself as a versatile performer. Seeing him on Broadway in ‘Take Me Out’ and getting a Tony nomination was amazing, and I loved his recent appearance in ‘Only Murders in the Building’ with Martin Short and Steve Martin. It’s also cool that he’s directing TV episodes and starring in movies like ‘Your Place or Mine’ – he’s clearly someone with a lot of talent and drive!
Jessica Capshaw
Jessica Capshaw is known for her ten-year role as Dr. Arizona Robbins on a popular medical drama. After leaving the show, she took some time to focus on her family, then returned to acting with the romantic comedy ‘Holidate’. More recently, she appeared in the first season of the series ‘Tell Me Lies’ and teamed up with a former colleague, Camilla Luddington, to launch a podcast called ‘Call It What It Is’.
Isaiah Washington
Isaiah Washington left the show ‘Grey’s Anatomy’ after season three, where he played heart surgeon Dr. Preston Burke. He then became a main character in the sci-fi series ‘The 100,’ playing Thelonious Jaha. More recently, he appeared in the highly praised drama ‘P-Valley’ as Mayor Tydell Ruffin. Washington just finished directing and starring in the western movie ‘Corsicana,’ where he played the role of Bass Reeves.
Kate Walsh
Kate Walsh first left ‘Grey’s Anatomy’ to star in its spinoff, ‘Private Practice,’ playing Dr. Addison Montgomery. Since then, she’s become well-known for her work in shows like ’13 Reasons Why’ and ‘The Umbrella Academy.’ Currently, she plays Madeline Wheeler in the comedy ‘Emily in Paris,’ and she still makes occasional guest appearances on ‘Grey’s Anatomy’ when her schedule allows.
Sarah Drew
Sarah Drew is known for her nine seasons playing Dr. April Kepner on a popular medical drama, after which her character left to help provide healthcare to people experiencing homelessness. Since then, she’s appeared in the thriller series ‘Cruel Summer’ and the comedy ‘Amber Brown’. Drew often stars in and produces TV movies for Hallmark, such as ‘Guiding Emily’, and recently took on a leading role in the drama ‘Mistletoe Murders’.
Jeffrey Dean Morgan
Jeffrey Dean Morgan first gained attention for his touching role as Denny Duquette, a patient with a serious heart condition, before the character’s untimely death. He then became widely known for playing the menacing villain Negan in the hit series ‘The Walking Dead’. Morgan continued as Negan in the show’s spinoff, ‘The Walking Dead: Dead City’, which takes place in Manhattan. Most recently, he joined the cast of the satirical superhero series ‘The Boys’ for its fourth season.
Jerrika Hinton
Jerrika Hinton spent five seasons on a medical drama playing Dr. Stephanie Edwards, a skilled surgical resident. Following her departure, she quickly landed a leading role in the series ‘Here and Now’. Later, she appeared as Millie Morris in the drama ‘Hunters’ with Al Pacino. Most recently, she starred in the limited series ‘A Man in Full’, which was adapted from the novel by Tom Wolfe.
Martin Henderson
Martin Henderson is an actor who gained recognition for his roles in several popular projects. He played Dr. Nathan Riggs on ‘Grey’s Anatomy’ and starred as Jack Sheridan in the romantic series ‘Virgin River’. He also appeared in the horror film ‘X’ as Wayne Gilroy. Currently, he continues to work consistently on film and television productions in both the US and New Zealand.
Giacomo Gianniotti
Giacomo Gianniotti was known for playing Dr. Andrew DeLuca on a TV show until his character was killed while chasing a human trafficker. Beyond that role, he’s also lent his voice to the animated film ‘Luca’ and starred in the Italian movie ‘Diabolik’. More recently, he’s taken on leading roles, including Cole Ellis in the series ‘Wild Cards’ and appearing with Zoe Saldana in the limited series ‘From Scratch’.
Scott Foley
Scott Foley is known for his roles in several popular television shows and films. He first gained recognition playing Henry Burton on Grey’s Anatomy, a character who married Dr. Teddy Altman. He later starred as Jake Ballard in the political series Scandal, and went on to lead the action comedy Whiskey Cavalier. More recently, he appeared in the limited series The Big Leap, the romantic comedy Puppy Love, and the political drama The Girls on the Bus.
Kelly McCreary
Kelly McCreary is an actress best known for her nine-season role as Dr. Maggie Pierce, a skilled heart and chest surgeon, before her character moved to a new show set in Chicago. Beyond television, she’s a voice actor in animated series like ‘Harvey Girls Forever’ and ‘Craig of the Creek’, and recently appeared in ‘Big Mouth’ and ‘Station 19’. McCreary also dedicates her time to both theater and advocating for social justice causes.
Greg Germann
Greg Germann played Dr. Tom Koracick, a neurosurgeon, on the show for four seasons before moving on. He later joined the cast of ‘Firefly Lane,’ where he worked with Katherine Heigl again. Germann also appeared in season two of the horror series ‘Them,’ and he continues to act in theater and make guest appearances on television.
Read More
- Broadcom’s Quiet Challenge to Nvidia’s AI Empire
- Gold Rate Forecast
- METH PREDICTION. METH cryptocurrency
- How to Do Sculptor Without a Future in KCD2 – Get 3 Sculptor’s Things
- Trump Ends Shutdown-And the Drama! 🎭💸 (Spoiler: No One Wins)
- Investing Dividends: A Contemporary Approach to Timeless Principles
- South Korea’s KRW1 Stablecoin Shocks the Financial World: A Game-Changer?
- Shiba Inu’s Netflow Drama: Bulls, Bears, and 147 Trillion SHIB
- Ether’s Future: 4 Things That Could Make or Break Its Bullish Comeback in 2025
- Hedera’s Latest Move: WBTC Joins the DeFi Party, Let the Bitcoin Liquidity Games Begin!
2025-11-19 17:46