CRISPR’s Gamble: A Contrarian’s Playbook
CRISPR’s Casgevy, the first CRISPR-based gene-editing therapy, is a flicker in the dark-a match struck in a room full of wet paper. Approved for sickle cell and beta-thalassemia, it’s a marvel. But it’s also a $2.2 million albatross, strung up on a scaffold of authorized treatment centers and third-party payers who’d rather argue over reimbursement than fund a miracle.