Beyond the Scan: Smarter Imaging for Alzheimer’s Detection

New research reveals that carefully crafted self-supervised learning techniques can unlock more sensitive brain imaging biomarkers for earlier and more accurate Alzheimer’s disease diagnosis.

![The study investigates how language model-based agents can be augmented with external oracles-[latex]\mathcal{O}^{\text{state}}[/latex] for summarizing state, [latex]\mathcal{O}^{\text{plan}}[/latex] for hinting waypoints, and [latex]\mathcal{O}^{\text{history}}[/latex] for rewriting task descriptions-to navigate multi-turn tasks, effectively pruning historical context and enabling agents to make decisions independent of prior steps within a Markov decision process.](https://arxiv.org/html/2601.16649v1/x1.png)




![A neural network’s internal logic is exposed through the construction of a neural graph-derived directly from its architecture-where the importance of each connection is quantified by a neural curvature [latex]\kappa\_{N}(u,v,x)[/latex] calculated across a calibration set [latex]\mathcal{D}[/latex], ultimately allowing for a ranking of connections based on their influence.](https://arxiv.org/html/2601.16366v1/img/overview.png)
